BDBM14775 3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide::3-cyclopentyloxy-N-(3,5-dichloropyridin-4-yl)-4-methoxy-benzamide::CHEMBL42126::Cpodpmb::Piclamilast::RPR-73401

SMILES COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(Cl)cncc1Cl

InChI Key InChIKey=RRRUXBQSQLKHEL-UHFFFAOYSA-N

Data  11 KI  39 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14775   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  3.80nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair